Smoke weed, save a brain cell? Maybe so, according to a recent study that linked THC to reduction in Alzheimer’s symptoms among patients. So much for that D.A.R.E.* working out, eh, Nancy Reagan?
From the abstract
“Alzheimer’s disease is the leading cause of dementia among the elderly, and with the ever-increasing size of this population, cases of Alzheimer’s disease are expected to triple over the next 50 years. Consequently, the development of treatments that slow or halt the disease progression have become imperative to both improve the quality of life for patients as well as reduce the health care costs attributable to Alzheimer’s disease. Here, we demonstrate that the active component of marijuana, Δ9-tetrahydrocannabinol (THC), competitively inhibits the enzyme acetylcholinesterase (AChE) as well as prevents AChE-induced amyloid β-peptide (Aβ) aggregation, the key pathological marker of Alzheimer’s disease. Computational modeling of the THC-AChE interaction revealed that THC binds in the peripheral anionic site of AChE, the critical region involved in amyloidgenesis. Compared to currently approved drugs prescribed for the treatment of Alzheimer’s disease, THC is a considerably superior inhibitor of Aβ aggregation, and this study provides a previously unrecognized molecular mechanism through which cannabinoid molecules may directly impact the progression of this debilitating disease.”
*Drug Abuse Resistance Education, a governmet program pushed like crack to grade schoolers in the eighties
Love this. I often feel this way while researching. Via reddit.
How cute is this notepad from organize.com?
I hope to do at least one homemade gift per person this Christmas, but this notepad would make a great stocking stuffer for that one person who either hasn’t joined twitter or can’t stop tweeting.
Is the iPad the most hated device ever? Perhaps not quite, but nonetheless an interesting read. Article by Mike Elgan. Via reddit.
Vice magazine has taken time out from overglamourizing hipsters to publish an op-ed on SOPA that actually makes sense written by Joshua Kopstein . Via Hacker News.
The Christian Science Monitor has a fascinating piece by writer Scott Peterson about how the Iranians may have hacked the GPS of the US drone they recently captured.
The Wall Street Journal has a cover story today, written by Margaret Coker and Paul Sonne, about how the Libyan government under Ghadafi monitored a journalist’s email with the help of a French tech company.
“In August 2010, Libyan journalist Khaled Mehiri shot an email to his editor at al-Jazeera proposing an article about the hollow nature of the Gadhafi regime’s anticorruption efforts.
Before the story was even written, the regime knew about it. Libyan security agents had intercepted the email, using an Internet-surveillance system purchased from a French company, Amesys.”
Read more: http://online.wsj.com/article/SB10001424052970203764804577056230832805896.html#ixzz1gYtHdbyk
Thinkgeek.com has some fun geek gift wrap:
Considering this hair color:
I hope it comes out dark enough!